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anastral spindle assembly
Term Information
Accession
GO:0055048
Name
anastral spindle assembly
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.
Source:
GOC:expert_rg,
GOC:tb,
GOC:mtg_sensu,
PMID:15034926
Link
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Link
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Link
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