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Term Information

Accession
GO:0052720
Name
class II DNA-(apurinic or apyrimidinic site) endonuclease activity
Ontology
molecular_function
Synonyms
class II DNA-(apurinic or apyrimidinic site) lyase activity
Alternate IDs
GO:0140079
Definition
Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Source: PMID:19401441
Comment
Class II AP endonuclease is a nuclease, but not Class I, III and IV.
History
See term history for GO:0052720 at QuickGO
Subset
None
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Parents of class II DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0052720)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
class II DNA-(apurinic or apyrimidinic site) endonuclease activity [is_a relation] is_a  DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)
class II DNA-(apurinic or apyrimidinic site) endonuclease activity [is_a relation] is_a  endodeoxyribonuclease activity, producing 5'-phosphomonoesters (GO:0016888)

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