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lipopolysaccharide receptor complex
Term Information
Accession
GO:0046696
Name
lipopolysaccharide receptor complex
Ontology
cellular_component
Synonyms
LPS receptor complex
Alternate IDs
None
Definition
A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.
Source:PMID:9665271,
PMID:11706042
Comment
Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of.
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