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aflatoxin catabolic process

Term Information

Accession
GO:0046223
Name
aflatoxin catabolic process
Ontology
biological_process
Synonyms
aflatoxin breakdown, aflatoxin catabolism, aflatoxin degradation
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. Source: PMID:20807200, GOC:ai
Comment
None
History
See term history for GO:0046223 at QuickGO
Subset
None
Feedback
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Parents of aflatoxin catabolic process (GO:0046223)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aflatoxin catabolic process [is_a relation] is_a  aflatoxin metabolic process (GO:0046222)
aflatoxin catabolic process [is_a relation] is_a  mycotoxin catabolic process (GO:0043387)
aflatoxin catabolic process [is_a relation] is_a  organic heteropentacyclic compound catabolic process (GO:1901377)
Children of aflatoxin catabolic process (GO:0046223)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aflatoxin reductase (coenzyme F420) activity (GO:0052807) [BFO:0000050 relation] BFO:0000050  aflatoxin catabolic process
None.