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Term Information

Accession
GO:0045064
Name
T-helper 2 cell differentiation
Ontology
biological_process
Synonyms
T-helper 2 cell development
Alternate IDs
None
Definition
The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. Source: GOC:ebc, CL:0000546
Comment
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0045064 at QuickGO
Subset
None
Feedback
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Parents of T-helper 2 cell differentiation (GO:0045064)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
T-helper 2 cell differentiation [is_a relation] is_a  T-helper cell differentiation (GO:0042093)
T-helper 2 cell differentiation [BFO:0000050 relation] BFO:0000050  type 2 immune response (GO:0042092)
Children of T-helper 2 cell differentiation (GO:0045064)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of T-helper 2 cell differentiation (GO:0045629) [RO:0002212 relation] RO:0002212  T-helper 2 cell differentiation
positive regulation of T-helper 2 cell differentiation (GO:0045630) [RO:0002213 relation] RO:0002213  T-helper 2 cell differentiation
regulation of T-helper 2 cell differentiation (GO:0045628) [RO:0002211 relation] RO:0002211  T-helper 2 cell differentiation
T-helper 2 cell lineage commitment (GO:0002297) [BFO:0000050 relation] BFO:0000050  T-helper 2 cell differentiation
None.