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killing by virus of host cell by post-segregational killing

Term Information

Accession
GO:0044696
Name
killing by virus of host cell by post-segregational killing
Ontology
biological_process
Synonyms
killing by virus of host cell by PSK, killing by virus of host cell by toxin-antitoxin system
Alternate IDs
None
Definition
The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes. Source: PMID:11222604, Wikipedia:Toxin-antitoxin_system, GOC:jl, GOC:bf
Comment
Note that this process occurs after the cell division partitioning event.
History
See term history for GO:0044696 at QuickGO
Subset
None
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Parents of killing by virus of host cell by post-segregational killing (GO:0044696)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
killing by virus of host cell by post-segregational killing [is_a relation] is_a  killing by symbiont of host cells (GO:0001907)

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