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Term Information

Accession
GO:0044027
Name
negative regulation of gene expression via CpG island methylation
Ontology
biological_process
Synonyms
DNA hypermethylation of CpG island, epigenetic regulation of gene expression via CpG island hypermethylation, hypermethylation of CpG island, negative regulation of gene expression via CpG island hypermethylation, negative regulation of gene expression via chromosomal DNA cytosine methylation, maintenance of DNA methylation
Alternate IDs
None
Definition
An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. Source: Wikipedia:Cpg_island, PMID:11898023, GOC:jl
Comment
None
History
See term history for GO:0044027 at QuickGO
Subset
None
Feedback
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Parents of negative regulation of gene expression via CpG island methylation (GO:0044027)
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negative regulation of gene expression via CpG island methylation [is_a relation] is_a  negative regulation of gene expression, epigenetic (GO:0045814)

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