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apoptosome
Term Information
Accession
GO:0043293
Name
apoptosome
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Source:PMID:10428850,
PMID:12176339,
PMID:11406413,
GOC:mtg_apoptosis,
PMID:15189137
Link
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Link
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Link
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