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macrophage activation

Term Information

Accession
GO:0042116
Name
macrophage activation
Ontology
biological_process
Synonyms
macrophage polarization
Alternate IDs
None
Definition
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. Source: GOC:mgi_curators, PMID:14506301, ISBN:0781735149
Comment
None
History
See term history for GO:0042116 at QuickGO
Subset
None
Feedback
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Parents of macrophage activation (GO:0042116)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
macrophage activation [is_a relation] is_a  myeloid leukocyte activation (GO:0002274)
Children of macrophage activation (GO:0042116)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of macrophage activation (GO:0043031) [RO:0002212 relation] RO:0002212  macrophage activation
positive regulation of macrophage activation (GO:0043032) [RO:0002213 relation] RO:0002213  macrophage activation
microglial cell activation (GO:0001774) [is_a relation] is_a  macrophage activation
macrophage activation involved in immune response (GO:0002281) [is_a relation] is_a  macrophage activation
regulation of macrophage activation (GO:0043030) [RO:0002211 relation] RO:0002211  macrophage activation
None.