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Term Information

Accession
GO:0039573
Name
suppression by virus of host complement activation
Ontology
biological_process
Synonyms
inhibition of host complement activation by virus, inhibition of host complement cascade by virus, inhibition of host complement factors by virus
Alternate IDs
None
Definition
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase. Source: PMID:7745740, UniProtKB-KW:KW-1087, VZ:811, PMID:21191012
Comment
None
History
See term history for GO:0039573 at QuickGO
Subset
None
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Parents of suppression by virus of host complement activation (GO:0039573)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
suppression by virus of host complement activation [RO:0002212 relation] RO:0002212  complement activation (GO:0006956)
suppression by virus of host complement activation [is_a relation] is_a  modulation by virus of host immune response (GO:0075528)
suppression by virus of host complement activation [is_a relation] is_a  mitigation of host antiviral defense response (GO:0019049)

This term has no children.

VZ
811