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Term Information

Accession
GO:0038133
Name
ERBB2-ERBB3 signaling pathway
Ontology
biological_process
Synonyms
ERBB2-ERBB3 signalling pathway, HER2-HER3 signaling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission. Source: GOC:signaling, Reactome:R-HSA-1963589, PMID:16460914
Comment
None
History
See term history for GO:0038133 at QuickGO
Subset
None
Feedback
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Parents of ERBB2-ERBB3 signaling pathway (GO:0038133)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ERBB2-ERBB3 signaling pathway [is_a relation] is_a  ERBB2 signaling pathway (GO:0038128)
ERBB2-ERBB3 signaling pathway [is_a relation] is_a  ERBB3 signaling pathway (GO:0038129)

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None.