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Term Information

Accession
GO:0036398
Name
TCR signalosome
Ontology
cellular_component
Synonyms
LAT signalosome, linker for activation of T cells signalosome
Alternate IDs
None
Definition
A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology. Source: GOC:krc, PMID:22426112, PMID:17534068, PMID:20107804
Comment
None
History
See term history for GO:0036398 at QuickGO
Subset
None
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Parents of TCR signalosome (GO:0036398)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
TCR signalosome [BFO:0000051 relation] BFO:0000051  T cell receptor complex (GO:0042101)
TCR signalosome [is_a relation] is_a  protein-containing complex (GO:0032991)

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