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RNA N6-methyladenosine methyltransferase complex

Term Information

Accession
GO:0036396
Name
RNA N6-methyladenosine methyltransferase complex
Ontology
cellular_component
Synonyms
Mum2, Ime4, and Slz1 complex, WMM complex, METTL3-METTL14-WTAP methyltransferase complex, MIS complex, m(6)A writer complex, m6A methyltransferase complex
Alternate IDs
None
Definition
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). Source: PMID:29547716, GOC:sp, PMID:24407421, GOC:dgf, PMID:29507755, PMID:29535189, PMID:24316715, PMID:22685417
Comment
None
History
See term history for GO:0036396 at QuickGO
Subset
None
Feedback
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Parents of RNA N6-methyladenosine methyltransferase complex (GO:0036396)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA N6-methyladenosine methyltransferase complex [is_a relation] is_a  mRNA editing complex (GO:0045293)
RNA N6-methyladenosine methyltransferase complex [is_a relation] is_a  methyltransferase complex (GO:0034708)

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None.