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Term Information

Accession
GO:0036130
Name
prostaglandin H2 endoperoxidase reductase activity
Ontology
molecular_function
Synonyms
PGH2 9,11-endoperoxidase, PGH2 9-,11-endoperoxide reductase
Alternate IDs
None
Definition
Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate). Source: PMID:16475787, PMID:10622721, PMID:14979715, GOC:mw, KEGG_REACTION:R02264
Comment
None
History
See term history for GO:0036130 at QuickGO
Subset
None
Feedback
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Parents of prostaglandin H2 endoperoxidase reductase activity (GO:0036130)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
prostaglandin H2 endoperoxidase reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
prostaglandin H2 endoperoxidase reductase activity [BFO:0000050 relation] BFO:0000050  prostaglandin metabolic process (GO:0006693)

This term has no children.

KEGG_REACTION
R02264
Reactome
R-HSA-2161549
RHEA
45312