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mitophagy by induced vacuole formation
Term Information
Accession
GO:0035695
Name
mitophagy by induced vacuole formation
Ontology
biological_process
Synonyms
MIV-mediated mitophagy
Alternate IDs
None
Definition
The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
Source:
GOC:autophagy,
GOC:sp,
GOC:bf,
PMID:21264228
Comment
In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
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