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Term Information

Accession
GO:0035695
Name
mitophagy by induced vacuole formation
Ontology
biological_process
Synonyms
MIV-mediated mitophagy
Alternate IDs
None
Definition
The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes. Source: GOC:autophagy, GOC:sp, GOC:bf, PMID:21264228
Comment
In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
History
See term history for GO:0035695 at QuickGO
Subset
None
Feedback
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Parents of mitophagy by induced vacuole formation (GO:0035695)
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mitophagy by induced vacuole formation [is_a relation] is_a  autophagy of mitochondrion (GO:0000422)

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