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![[Inferred is_a relation]](http://draco.cyverse.org/static/images/is_a.gif "Inferred is_a relation")
BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
![[Inferred related_to relation]](http://draco.cyverse.org/static/images/related_to.gif "Inferred related_to relation")
GO:0050896 response to stimulus
GO:0051716 cellular response to stimulus
GO:0050789 regulation of biological process
GO:0042221 response to chemical
GO:0007154 cell communication
GO:0070887 cellular response to chemical stimulus
GO:0050794 regulation of cellular process
GO:0010033 response to organic substance
GO:0023052 signaling
GO:0071310 cellular response to organic substance
GO:0034097 response to cytokine
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0071345 cellular response to cytokine stimulus
GO:0070673 response to interleukin-18
GO:0071351 cellular response to interleukin-18
GO:0019221 cytokine-mediated signaling pathway
![[Current term]](http://draco.cyverse.org/static/images/term_lineage_wedge.png "Current term")
GO:0035655 interleukin-18-mediated signaling pathway
![[part_of relation]](http://draco.cyverse.org/static/images/part_of.gif "part_of relation")
GO:0042008 interleukin-18 receptor activity
![[negatively_regulates relation]](http://draco.cyverse.org/static/images/negatively_regulates.gif "negatively_regulates relation")
GO:2000493 negative regulation of interleukin-18-mediated signaling pathway
![[positively_regulates relation]](http://draco.cyverse.org/static/images/positively_regulates.gif "positively_regulates relation")
GO:2000494 positive regulation of interleukin-18-mediated signaling pathway
![[regulates relation]](http://draco.cyverse.org/static/images/regulates.gif "regulates relation")
GO:2000492 regulation of interleukin-18-mediated signaling pathway
subject![[Reorder by subject]](http://draco.cyverse.org/static/images/reorder.gif "Reorder by subject") |
relation |
object |
|---|---|---|
| interleukin-18-mediated signaling pathway |
![[BFO:0000050 relation]](http://draco.cyverse.org/static/images/BFO:0000050.gif "BFO:0000050 relation") BFO:0000050
|
cellular response to interleukin-18 (GO:0071351) |
| interleukin-18-mediated signaling pathway |
is_a
|
cytokine-mediated signaling pathway (GO:0019221) |
| subject |
relation |
object |
|---|---|---|
| negative regulation of interleukin-18-mediated signaling pathway (GO:2000493) |
![[RO:0002212 relation]](http://draco.cyverse.org/static/images/RO:0002212.gif "RO:0002212 relation") RO:0002212
|
interleukin-18-mediated signaling pathway |
| regulation of interleukin-18-mediated signaling pathway (GO:2000492) |
![[RO:0002211 relation]](http://draco.cyverse.org/static/images/RO:0002211.gif "RO:0002211 relation") RO:0002211
|
interleukin-18-mediated signaling pathway |
| interleukin-18 receptor activity (GO:0042008) |
BFO:0000050
|
interleukin-18-mediated signaling pathway |
| positive regulation of interleukin-18-mediated signaling pathway (GO:2000494) |
![[RO:0002213 relation]](http://draco.cyverse.org/static/images/RO:0002213.gif "RO:0002213 relation") RO:0002213
|
interleukin-18-mediated signaling pathway |