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Notch receptor processing, ligand-independent
Term Information
Accession
GO:0035334
Name
Notch receptor processing, ligand-independent
Ontology
biological_process
Synonyms
Notch S1 cleavage
Alternate IDs
None
Definition
The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.
Source:PMID:12651094,
GOC:bf
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