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Hedgehog signaling complex
Term Information
Accession
GO:0035301
Name
Hedgehog signaling complex
Ontology
cellular_component
Synonyms
HSC, Hedgehog signalling complex
Alternate IDs
None
Definition
A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).
Source:PMID:15057936,
PMID:10825151
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