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Term Information

Accession
GO:0035278
Name
miRNA-mediated gene silencing by inhibition of translation
Ontology
biological_process
Synonyms
down regulation of translation involved in gene silencing by miRNA, down-regulation of translation involved in gene silencing by miRNA, downregulation of translation involved in gene silencing by miRNA, gene silencing by miRNA, negative regulation of translation, miRNA mediated inhibition of translation, negative regulation of translation involved in gene silencing by microRNA, miRNA-mediated gene silencing, negative regulation of translation, inhibition of translation involved in gene silencing by miRNA
Alternate IDs
None
Definition
An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs. Source: PMID:15196554, PMID:14744438
Comment
None
History
See term history for GO:0035278 at QuickGO
Subset
None
Feedback
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Parents of miRNA-mediated gene silencing by inhibition of translation (GO:0035278)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
miRNA-mediated gene silencing by inhibition of translation [is_a relation] is_a  negative regulation of translation (GO:0017148)
miRNA-mediated gene silencing by inhibition of translation [is_a relation] is_a  miRNA-mediated gene silencing (GO:0035195)

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None.