protein arginine omega-N symmetric methylase activity, protein arginine omega-N symmetric methyltransferase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming), type II PRMT activity, type II protein arginine methyltransferase activity
Alternate IDs
None
Definition
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.
Source:EC:2.1.1.320,
PMID:14705965,
RESID:AA0067,
RESID:AA0069
Comment
Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'.
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