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interchromatin granule
Term Information
Accession
GO:0035061
Name
interchromatin granule
Ontology
cellular_component
Synonyms
ICG
Alternate IDs
None
Definition
A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
Source:
GOC:bf,
PMID:10984439
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