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CFTR-NHERF-ezrin complex
Term Information
Accession
GO:0034662
Name
CFTR-NHERF-ezrin complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.
Source:PMID:16926444,
PMID:16129695,
PMID:16798722
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