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DNA negative supercoiling activity
Term Information
Accession
GO:0034335
Name
DNA negative supercoiling activity
Ontology
molecular_function
Synonyms
DNA gyrase activity, DNA-gyrase activity
Alternate IDs
None
Definition
Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.
Source:
GOC:krc,
WikiPedia:DNA_gyrase,
GOC:mah,
GOC:bhm
Link
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Link
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Link
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