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HULC complex
Term Information
Accession
GO:0033503
Name
HULC complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A ubiquitin ligase complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp6, Shf1, Brl2/Rfp1 and Brl1/Rfp2.
Source:PMID:17374714,
GOC:mah,
PMID:17363370
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