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Lsd1/2 complex
Term Information
Accession
GO:0033193
Name
Lsd1/2 complex
Ontology
cellular_component
Synonyms
SAPHIRE complex, Swm complex, Swm1/2 complex
Alternate IDs
None
Definition
A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.
Source:PMID:17434129,
PMID:17440621,
GOC:vw,
PMID:17371846
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