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CAF-1 complex
Term Information
Accession
GO:0033186
Name
CAF-1 complex
Ontology
cellular_component
Synonyms
chromatin assembly factor 1 complex
Alternate IDs
None
Definition
A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.
Source:PMID:17083276,
PMID:17065558
Comment
In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90.
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