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Term Information

Accession
GO:0032508
Name
DNA duplex unwinding
Ontology
biological_process
Synonyms
DNA unwinding, duplex DNA melting
Alternate IDs
None
Definition
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands. Source: GOC:isa_complete, GOC:mah
Comment
Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
History
See term history for GO:0032508 at QuickGO
Subset
None
Feedback
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Parents of DNA duplex unwinding (GO:0032508)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA duplex unwinding [is_a relation] is_a  DNA geometric change (GO:0032392)
Children of DNA duplex unwinding (GO:0032508)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of DNA duplex unwinding (GO:1905463) [RO:0002212 relation] RO:0002212  DNA duplex unwinding
positive regulation of DNA duplex unwinding (GO:1905464) [RO:0002213 relation] RO:0002213  DNA duplex unwinding
regulation of DNA duplex unwinding (GO:1905462) [RO:0002211 relation] RO:0002211  DNA duplex unwinding
DNA unwinding involved in DNA replication (GO:0006268) [is_a relation] is_a  DNA duplex unwinding
nucleotide-excision repair, DNA duplex unwinding (GO:0000717) [is_a relation] is_a  DNA duplex unwinding
DNA helicase activity (GO:0003678) [BFO:0000050 relation] BFO:0000050  DNA duplex unwinding
None.