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purine-rich negative regulatory element binding
Term Information
Accession
GO:0032422
Name
purine-rich negative regulatory element binding
Ontology
molecular_function
Synonyms
PNR element binding
Alternate IDs
None
Definition
Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
Source:PMID:9819411,
GOC:mah
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