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Term Information

Accession
GO:0031052
Name
programmed DNA elimination by chromosome breakage
Ontology
biological_process
Synonyms
chromosome breakage
Alternate IDs
None
Definition
Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage. Source: PMID:32165395, PMID:15956677, GOC:ns, PMID:25303953
Comment
Note that this term refers to breakage of chromosomes during normal DNA well characterized in ciliates but also present in many vertebrates; it is not to be used for DNA damage or other abnormal occurrences.
History
See term history for GO:0031052 at QuickGO
Subset
None
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Parents of programmed DNA elimination by chromosome breakage (GO:0031052)
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programmed DNA elimination by chromosome breakage [is_a relation] is_a  programmed DNA elimination (GO:0031049)

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