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Term Information

Accession
GO:0030175
Name
filopodium
Ontology
cellular_component
Synonyms
None
Alternate IDs
GO:0030028
Definition
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. Source: GOC:pr, GOC:mah, ISBN:0815316194
Comment
A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
History
See term history for GO:0030175 at QuickGO
Subset
goslim_pir
Feedback
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Parents of filopodium (GO:0030175)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
filopodium [is_a relation] is_a  actin-based cell projection (GO:0098858)
Children of filopodium (GO:0030175)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
growth cone filopodium (GO:1990812) [is_a relation] is_a  filopodium
dendritic filopodium (GO:1902737) [is_a relation] is_a  filopodium
actin filament bundle of filopodium (GO:0098861) [BFO:0000050 relation] BFO:0000050  filopodium
filopodium membrane (GO:0031527) [BFO:0000050 relation] BFO:0000050  filopodium
filopodium tip (GO:0032433) [BFO:0000050 relation] BFO:0000050  filopodium
NIF_Subcellular
sao1046371754
Wikipedia
Filopodia