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AP-1 adaptor complex
Term Information
Accession
GO:0030121
Name
AP-1 adaptor complex
Ontology
cellular_component
Synonyms
HA1, HA1 clathrin adaptor, AP-1 related adapter complex
Alternate IDs
None
Definition
A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
Source:PMID:10611976,
GOC:mah,
PMID:21097499
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