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Term Information

Accession
GO:0030014
Name
CCR4-NOT complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8. Source: PMID:30601114, GOC:sart, PMID:11113136, PMID:22785621, PMID:11239395
Comment
None
History
See term history for GO:0030014 at QuickGO
Subset
None
Feedback
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Parents of CCR4-NOT complex (GO:0030014)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
CCR4-NOT complex [is_a relation] is_a  intracellular protein-containing complex (GO:0140535)
Children of CCR4-NOT complex (GO:0030014)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
CCR4-NOT core complex (GO:0030015) [BFO:0000050 relation] BFO:0000050  CCR4-NOT complex
None.