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CCR4-NOT complex
Term Information
Accession
GO:0030014
Name
CCR4-NOT complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.
Source:PMID:30601114,
GOC:sart,
PMID:11113136,
PMID:22785621,
PMID:11239395
Link
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Link
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Link
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