Planteome: Term Details for "type I site-specific deoxyribonuclease complex" (GO:0019812)

Term Information

Accession: GO:0019812
Name: type I site-specific deoxyribonuclease complex
Ontology: cellular_component
Synonyms: type I restriction enzyme complex
Alternate IDs: None
Definition: A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell. Source: PMID:15788748, PMID:12654995
Comment: None
History: See term history for GO:0019812 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to type I site-specific deoxyribonuclease complex.; Link to all direct and indirect annotations to type I site-specific deoxyribonuclease complex.; Link to all direct and indirect annotations download (limited to first 10,000) for type I site-specific deoxyribonuclease complex.
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GO:0005575 cellular_component
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0110165 cellular anatomical entity
GO:0140535 intracellular protein-containing complex
GO:1905348 endonuclease complex
GO:0005622 intracellular anatomical structure
GO:0005737 cytoplasm
GO:1905347 endodeoxyribonuclease complex
GO:0019812 type I site-specific deoxyribonuclease complex

Parents of type I site-specific deoxyribonuclease complex (GO:0019812)

subject	relation	object
type I site-specific deoxyribonuclease complex	is_a	endodeoxyribonuclease complex (GO:1905347)
type I site-specific deoxyribonuclease complex	BFO:0000050	cytoplasm (GO:0005737)

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type I site-specific deoxyribonuclease complex

Term Information

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Parents of type I site-specific deoxyribonuclease complex (GO:0019812)

None.