Planteome: Term Details for "reductive tricarboxylic acid cycle" (GO:0019643)

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Term Information

Accession: GO:0019643
Name: reductive tricarboxylic acid cycle
Ontology: biological_process
Synonyms: reductive Kreb's cycle, reductive TCA cycle, reductive carboxylate cycle, reductive carboxylic acid cycle, reductive citric acid pathway
Alternate IDs: GO:0019644
Definition: A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate. Source: PMID:15838028, GOC:jl
Comment: None
History: See term history for GO:0019643 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to reductive tricarboxylic acid cycle.; Link to all direct and indirect annotations to reductive tricarboxylic acid cycle.; Link to all direct and indirect annotations download (limited to first 10,000) for reductive tricarboxylic acid cycle.
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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0015980 energy derivation by oxidation of organic compounds
GO:0045333 cellular respiration
GO:0009060 aerobic respiration
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0015977 carbon fixation
GO:0006099 tricarboxylic acid cycle
GO:0019643 reductive tricarboxylic acid cycle

Parents of reductive tricarboxylic acid cycle (GO:0019643)

subject	relation	object
reductive tricarboxylic acid cycle	is_a	tricarboxylic acid cycle (GO:0006099)
reductive tricarboxylic acid cycle	is_a	carbon fixation (GO:0015977)

This term has no children.

MetaCyc: REDCITCYC; P23-PWY