Planteome: Term Details for "glyoxalase III activity" (GO:0019172)

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Term Information

Accession: GO:0019172
Name: glyoxalase III activity
Ontology: molecular_function
Synonyms: (R)-lactate hydro-lyase, D-lactate dehydratase, glutathione-independent glyoxalase activity
Alternate IDs: None
Definition: Catalysis of the reaction: methylglyoxal + H2O = D-lactate. Source: PMID:7848303, GOC:mcc, PMID:21696459, RHEA:27754
Comment: Note that this term was reinstated from obsolete. Also note that this enzymatic activity converts methylglyoxal to D-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalyzed by EC:4.4.1.5 (lactoylglutathione lyase) and EC:3.1.2.6 (hydroxyacylglutathione hydrolase).
History: See term history for GO:0019172 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to glyoxalase III activity.; Link to all direct and indirect annotations to glyoxalase III activity.; Link to all direct and indirect annotations download (limited to first 10,000) for glyoxalase III activity.
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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044281 small molecule metabolic process
GO:0009058 biosynthetic process
GO:0006082 organic acid metabolic process
GO:0009056 catabolic process
GO:0044249 cellular biosynthetic process
GO:0003674 molecular_function
GO:1901576 organic substance biosynthetic process
GO:0043436 oxoacid metabolic process
GO:0044283 small molecule biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0003824 catalytic activity
GO:0006081 cellular aldehyde metabolic process
GO:0044248 cellular catabolic process
GO:0042180 cellular ketone metabolic process
GO:0016053 organic acid biosynthetic process
GO:1901575 organic substance catabolic process
GO:0044282 small molecule catabolic process
GO:0046185 aldehyde catabolic process
GO:0046394 carboxylic acid biosynthetic process
GO:0042182 ketone catabolic process
GO:0016829 lyase activity
GO:0009438 methylglyoxal metabolic process
GO:0032787 monocarboxylic acid metabolic process
GO:1901615 organic hydroxy compound metabolic process
GO:0016835 carbon-oxygen lyase activity
GO:0006089 lactate metabolic process
GO:0051596 methylglyoxal catabolic process
GO:0072330 monocarboxylic acid biosynthetic process
GO:1901617 organic hydroxy compound biosynthetic process
GO:0016836 hydro-lyase activity
GO:0019249 lactate biosynthetic process
GO:0061727 methylglyoxal catabolic process to lactate
GO:0019172 glyoxalase III activity

Parents of glyoxalase III activity (GO:0019172)

subject	relation	object
glyoxalase III activity	is_a	hydro-lyase activity (GO:0016836)
glyoxalase III activity	BFO:0000050	methylglyoxal catabolic process to lactate (GO:0061727)
glyoxalase III activity	BFO:0000050	lactate biosynthetic process (GO:0019249)

This term has no children.

EC: 4.2.1.130
MetaCyc: GLYOXIII-RXN
RHEA: 27754