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aminoacyl-tRNA synthetase multienzyme complex

Term Information

Accession
GO:0017101
Name
aminoacyl-tRNA synthetase multienzyme complex
Ontology
cellular_component
Synonyms
aminoacyl-tRNA synthetase complex, multisynthetase complex
Alternate IDs
None
Definition
A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates. Source: PMID:16169847, GOC:jl
Comment
None
History
See term history for GO:0017101 at QuickGO
Subset
None
Feedback
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Parents of aminoacyl-tRNA synthetase multienzyme complex (GO:0017101)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aminoacyl-tRNA synthetase multienzyme complex [is_a relation] is_a  intracellular protein-containing complex (GO:0140535)
aminoacyl-tRNA synthetase multienzyme complex [is_a relation] is_a  catalytic complex (GO:1902494)

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None.