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Term Information

Accession
GO:0016272
Name
prefoldin complex
Ontology
cellular_component
Synonyms
GIM complex
Alternate IDs
None
Definition
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. Source: PMID:9630229, GOC:jl, PMID:17384227, PMID:24068951
Comment
None
History
See term history for GO:0016272 at QuickGO
Subset
None
Link to all annotated objects annotated to prefoldin complex.
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Parents of prefoldin complex (GO:0016272)
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prefoldin complex [is_a relation] is_a  protein-containing complex (GO:0032991)

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Wikipedia
Prefoldin