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response to fluoxetine
Term Information
Accession
GO:0014076
Name
response to fluoxetine
Ontology
biological_process
Synonyms
response to SSRI, response to selective serotonin reuptake inhibitor
Alternate IDs
None
Definition
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
Source:
GOC:pr,
GOC:ef
Comment
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.
Link
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