You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is currently down for maintenance.

Term Information

Accession
GO:0009386
Name
translational attenuation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation. Source: PMID:15805513, PMID:15694341
Comment
None
History
See term history for GO:0009386 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of translational attenuation (GO:0009386)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
translational attenuation [is_a relation] is_a  regulation of translation (GO:0006417)

This term has no children.

None.