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excinuclease repair complex

Term Information

Accession
GO:0009380
Name
excinuclease repair complex
Ontology
cellular_component
Synonyms
UvrABC excinuclease complex, excinuclease ABC complex
Alternate IDs
None
Definition
Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap. Source: PMID:12145219, GOC:mah, GOC:mlg, PMID:15192705
Comment
None
History
See term history for GO:0009380 at QuickGO
Subset
None
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Parents of excinuclease repair complex (GO:0009380)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
excinuclease repair complex [is_a relation] is_a  endodeoxyribonuclease complex (GO:1905347)
excinuclease repair complex [is_a relation] is_a  DNA repair complex (GO:1990391)

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None.