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Term Information

Accession
GO:0009360
Name
DNA polymerase III complex
Ontology
cellular_component
Synonyms
DNA polymerase III holoenzyme complex
Alternate IDs
None
Definition
The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. Source: UniProt:P06710, PMID:12940977, PMID:11525729
Comment
None
History
See term history for GO:0009360 at QuickGO
Subset
None
Feedback
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Parents of DNA polymerase III complex (GO:0009360)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA polymerase III complex [is_a relation] is_a  DNA polymerase complex (GO:0042575)
Children of DNA polymerase III complex (GO:0009360)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytoplasmic replisome (GO:0043600) [BFO:0000051 relation] BFO:0000051  DNA polymerase III complex
DNA polymerase III, core complex (GO:0044776) [BFO:0000050 relation] BFO:0000050  DNA polymerase III complex
DNA polymerase III, beta sliding clamp processivity factor complex (GO:0044775) [BFO:0000050 relation] BFO:0000050  DNA polymerase III complex
DNA polymerase III, clamp loader complex (GO:0043846) [BFO:0000050 relation] BFO:0000050  DNA polymerase III complex
None.