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Term Information

Accession
GO:0008705
Name
methionine synthase activity
Ontology
molecular_function
Synonyms
5-methyltetrahydrofolate-homocysteine S-methyltransferase activity, 5-methyltetrahydrofolate--homocysteine S-methyltransferase activity, 5-methyltetrahydrofolate--homocysteine transmethylase activity, 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity, B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity, B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity, MetH, N(5)-methyltetrahydrofolate methyltransferase activity, N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity, N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity, N-methyltetrahydrofolate:L-homocysteine methyltransferase activity, N5-methyltetrahydrofolate methyltransferase activity, N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity, N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity, cobalamin-dependent methionine synthase activity, methionine synthase (cobalamin-dependent) activity, methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity, tetrahydrofolate methyltransferase activity, tetrahydropteroylglutamate methyltransferase activity, tetrahydropteroylglutamic methyltransferase activity, vitamin B12 methyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine. Source: EC:2.1.1.13, RHEA:11172
Comment
None
History
See term history for GO:0008705 at QuickGO
Subset
None
Feedback
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Parents of methionine synthase activity (GO:0008705)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
methionine synthase activity [is_a relation] is_a  S-methyltransferase activity (GO:0008172)
methionine synthase activity [BFO:0000050 relation] BFO:0000050  methionine biosynthetic process (GO:0009086)
methionine synthase activity [is_a relation] is_a  5-methyltetrahydrofolate-dependent methyltransferase activity (GO:0042084)

This term has no children.

EC
2.1.1.13
KEGG_REACTION
R00946
MetaCyc
HOMOCYSMETB12-RXN
Reactome
R-HSA-3149539
R-HSA-174374
RHEA
11172