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Term Information

Accession
GO:0008622
Name
epsilon DNA polymerase complex
Ontology
cellular_component
Synonyms
DNA polymerase epsilon complex
Alternate IDs
None
Definition
A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair. Source: PMID:15814431, PMID:9745046
Comment
None
History
See term history for GO:0008622 at QuickGO
Subset
None
Feedback
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Parents of epsilon DNA polymerase complex (GO:0008622)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epsilon DNA polymerase complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
epsilon DNA polymerase complex [BFO:0000050 relation] BFO:0000050  nuclear chromosome (GO:0000228)
epsilon DNA polymerase complex [is_a relation] is_a  DNA polymerase complex (GO:0042575)

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None.