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JUN kinase kinase activity
Term Information
Accession
GO:0008545
Name
JUN kinase kinase activity
Ontology
molecular_function
Synonyms
JNKK
Alternate IDs
None
Definition
Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.
Source:PMID:11790549,
GOC:bf,
PMID:11057897
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