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receptor-mediated endocytosis
Term Information
Accession
GO:0006898
Name
receptor-mediated endocytosis
Ontology
biological_process
Synonyms
receptor mediated endocytosis
Alternate IDs
None
Definition
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
Source:ISBN:0716731363,
GOC:mah
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