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protein retention in ER lumen
Term Information
Accession
GO:0006621
Name
protein retention in ER lumen
Ontology
biological_process
Synonyms
maintenance of protein location in ER lumen
Alternate IDs
None
Definition
The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
Source:ISBN:0716731363,
PMID:12972550
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