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Term Information

Accession
GO:0006601
Name
creatine biosynthetic process
Ontology
biological_process
Synonyms
creatine anabolism, creatine biosynthesis, creatine formation, creatine synthesis
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle. Source: MetaCyc:PWY-6158, MetaCyc:GLYCGREAT-PWY, GOC:mah
Comment
None
History
See term history for GO:0006601 at QuickGO
Subset
None
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Parents of creatine biosynthetic process (GO:0006601)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
creatine biosynthetic process [is_a relation] is_a  cellular modified amino acid biosynthetic process (GO:0042398)
creatine biosynthetic process [is_a relation] is_a  creatine metabolic process (GO:0006600)
creatine biosynthetic process [is_a relation] is_a  monocarboxylic acid biosynthetic process (GO:0072330)

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None.