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Term Information

Accession
GO:0005944
Name
phosphatidylinositol 3-kinase complex, class IB
Ontology
cellular_component
Synonyms
1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex, class IB PI3K complex, phosphoinositide 3-kinase complex, class IB, 1-phosphatidylinositol-4-phosphate kinase, class IB complex
Alternate IDs
GO:0035031
Definition
A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks. Source: PMID:9759495, PMID:9255069
Comment
None
History
See term history for GO:0005944 at QuickGO
Subset
None
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Parents of phosphatidylinositol 3-kinase complex, class IB (GO:0005944)
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phosphatidylinositol 3-kinase complex, class IB [is_a relation] is_a  phosphatidylinositol 3-kinase complex, class I (GO:0097651)

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