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Term Information

Accession
GO:0005943
Name
phosphatidylinositol 3-kinase complex, class IA
Ontology
cellular_component
Synonyms
1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex, 1-phosphatidylinositol-4-phosphate kinase, class IA complex, class IA PI3K complex, phosphoinositide 3-kinase complex, class IA
Alternate IDs
GO:0035030
Definition
A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways. Source: PMID:9759495, PMID:9255069
Comment
None
History
See term history for GO:0005943 at QuickGO
Subset
None
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Parents of phosphatidylinositol 3-kinase complex, class IA (GO:0005943)
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phosphatidylinositol 3-kinase complex, class IA [is_a relation] is_a  phosphatidylinositol 3-kinase complex, class I (GO:0097651)

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