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nuclear lamina
Term Information
Accession
GO:0005652
Name
nuclear lamina
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
Source:ISBN:0716731363,
ISBN:0198506732
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